Brain Fog
Supports mental clarity, focus, and quality of thinking under stress.
NAD+ Therapy in Easley, SC: Cellular Repair, Mental Clarity and Anti-Aging
Quick clinical injections that support cellular repair, mental clarity, and anti-aging
Treatment Time:About 15 minutes per visit
Onset:First effects within 24 to 72 hours
Duration:Weeks to months with maintenance injections
FDA Status:Compounded NAD+ for injection is permitted under USP standards. The FDA does not approve a specific NAD+ injection product.
What it is
Why NAD+ Therapy Feels Different
Beyond standard supplements
Most people reach a point where rest, sleep, and supplements only do so much. You feel foggy by mid-afternoon, recovery from workouts or stress takes longer than it used to, and the small fatigues add up. Some patients also come to us in early recovery from alcohol or substance use, looking for support that is medically supervised and grounded in real science. Standard energy drinks and even routine vitamin pills often miss the deeper, mitochondrial layer where this kind of fatigue lives.
NAD+ therapy targets that mitochondrial layer. Nicotinamide adenine dinucleotide is a coenzyme your cells use to make energy and to repair DNA. As we age, NAD+ levels naturally decline. By delivering NAD+ as a fast intramuscular or subcutaneous injection, we bypass digestion and bring this coenzyme to your tissues quickly. At Riverstone Wellness, Kristina Schafer designs each protocol around your goals: focus, recovery, anti-aging support, or post-acute recovery from substance use.
Treatment Timeline
Visit Time
About 15 minutes total
Injection Time
About 30 seconds, plus brief observation
First Effects
Within 24 to 72 hours
Loading Phase
Weekly injection for 4 weeks
Maintenance
Every 2 to 4 weeks as needed
What Is NAD+ Therapy?
The cellular coenzyme explained
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell. It plays a central role in mitochondrial energy production, DNA repair, and the activity of sirtuins, a family of proteins linked to longevity and metabolic health. Research published in the National Library of Medicine has shown that NAD+ levels decline with age and that this decline is associated with reduced mitochondrial function, neurodegeneration, and metabolic stress (PMID: 29514064).
How NAD+ Works
Once delivered, NAD+ enters cellular pathways that power the mitochondria, drive ATP production, and support DNA repair through enzymes called sirtuins and PARPs. Because oral NAD+ is largely broken down in digestion, parenteral delivery is one of the more direct ways to raise circulating levels. Compounded NAD+ for injection is permitted under USP standards when prepared by a licensed pharmacy.
How NAD+ Is Delivered at Riverstone
We use injections only. Riverstone Wellness offers NAD+ as a quick intramuscular or subcutaneous injection. We do not offer longer clinic-based NAD+ protocols. The injection itself takes about 30 seconds, with a brief observation period afterward. A typical visit, including check-in and clinical review, runs about 15 minutes from arrival to walk-out. Many patients describe this as a much easier delivery than the longer clinic protocols offered elsewhere, with similar weekly cadence during the loading phase.
What Happens During a Session
Kristina greets you, confirms your goals and any medication changes, and reviews your loading or maintenance plan. She prepares the NAD+ syringe at the dose she selected with you, cleans the injection site, and administers a small intramuscular or subcutaneous injection. You wait a few minutes for an observation period, then head back to your day.
Results and Duration
Most patients begin to notice changes within 24 to 72 hours of their first NAD+ injection, often described as a quieter mind and steadier energy. With a series of weekly injections during the loading phase, many report stronger focus, better sleep quality, and a sense of cellular renewal that builds week over week.
Benefits of NAD+ Therapy
What patients report
2000+ Satisfied patients
- 01
Cellular Energy
Targets mitochondrial energy production at the cellular level.
- 02
Mental Clarity
Many patients describe clearer thinking and a quieter mind.
- 03
Cognitive Performance
Supports steadier focus and concentration during demanding days.
- 04
Cellular Repair
Direct delivery of a coenzyme central to DNA and mitochondrial repair.
- 05
Anti-Aging Support
Pairs with lifestyle and longevity care to support healthy aging.
- 06
Recovery Support
Used alongside lifestyle and medical care for stress and substance use recovery.
NAD+ Injection vs Alternatives
How it compares
| Treatment | Mechanism | Time | Results | Duration | Downtime | Best For |
|---|---|---|---|---|---|---|
| NAD+ Injection (Riverstone) | Direct intramuscular or subcutaneous NAD+ to mitochondria and DNA repair pathways | About 15 minutes per visit | Felt within 24 to 72 hours, fuller benefit over a series | Weeks to months with maintenance | None | Cellular repair, clarity, recovery support |
| NAD+ Clinic Protocol Elsewhere (not offered) | Longer clinic-based delivery of NAD+ over multiple hours | 1 to 4 hours per visit | Felt within 24 to 72 hours, similar overall benefit | Weeks to months with maintenance | None | Patients who prefer a longer clinic protocol (not offered at Riverstone) |
| Oral NAD+ Precursors (NMN, NR) | Oral precursor that the body converts toward NAD+ | Daily capsule, no clinic visit | Subtle, gradual, dose dependent | Ongoing daily use | None | Maintenance and convenience |
| B12 Injection | Single-vitamin support for energy metabolism and red blood cell production | About 10 minutes per visit | Energy support, especially with documented deficiency | Weeks per dose | None | Confirmed B12 deficiency or supportive energy care |
| Lifestyle Alone | Sleep, exercise, nutrition, and stress management | Daily ongoing | Foundational, slow-building | As long as habits are sustained | None | Healthy adults with mild concerns and good baseline labs |
Who Is a Good Candidate for NAD+ Therapy?
Honest, individualized screening
NAD+ therapy is best suited for adults who are committed to a whole-person approach to wellness and who want to support cellular repair, mental clarity, or recovery alongside good sleep, nutrition, and movement. Kristina will review your medical history before recommending a plan.
Ideal Candidates for NAD+ Therapy
- Adults experiencing brain fog, mental fatigue, or low energy that is not explained by a clear medical cause
- Patients seeking anti-aging and longevity support as part of a broader wellness plan
- Athletes and high performers looking for adjunctive recovery support
- People in medically supervised recovery from alcohol or substance use who want supportive care
- Patients who prefer a quick, low-commitment injection over longer clinic protocols
- Patients pairing NAD+ with sermorelin therapy in Easley, SC or other Riverstone wellness services
Who Should Wait or Avoid NAD+ Therapy
- People who are pregnant or breastfeeding
- Patients with active infection at the planned injection site
- Anyone with a known allergy to NAD+ or any compounded ingredient in the formulation
- Patients with severe cardiovascular, kidney, or liver disease, who may need specialist clearance first
- Anyone seeking NAD+ as a substitute for evaluation and treatment of a medical condition
If you are unsure whether NAD+ therapy is right for you, we will tell you honestly and recommend a different path when that is the better answer.
What an NAD+ Therapy Visit Looks Like
Step by step with Kristina
Consultation
Kristina reviews your goals, medications, and history to confirm NAD+ is appropriate for you.
Lab Review
She reviews any baseline labs and discusses dose, loading schedule, and maintenance plan.
Injection
Kristina cleans the site and administers a small intramuscular or subcutaneous injection in about 30 seconds.
Brief Observation
You wait a few minutes for a short clinical check before heading back to your day.
Aftercare and Follow-Up
Kristina shares hydration, sleep, and follow-up guidance and confirms your next injection.
Side Effects and Safety
What to know
-
Common, Dose-Related Effects
NAD+ injections are generally well tolerated when delivered at clinically appropriate doses and under supervision. The most common side effects are dose related and ease quickly after the injection is complete. Possible effects include flushing, chest tightness or pressure, nausea, abdominal cramping, headache, lightheadedness, and a feeling of warmth or pressure in the head during administration.
-
Less Common Reactions
Soreness, redness, or bruising at the injection site is also possible. More serious reactions are uncommon. Rarely, patients can experience an allergic reaction, significant blood pressure changes, or vasovagal symptoms. We mitigate this by taking a thorough history, selecting an appropriate dose for your size and goals, and observing you for several minutes after each injection visit.
-
Who Should Not Receive NAD+
NAD+ therapy is not appropriate during pregnancy or breastfeeding, with active infection at the injection site, or with certain heart, kidney, or liver conditions without clearance. Kristina reviews your full medical history, current medications, and supplements before your first injection. Call us right away for chest pain, shortness of breath, fainting, or any reaction that worries you after your visit.
Cost of NAD+ Therapy in Easley, SC
Transparent package pricing
NAD+ therapy at Riverstone Wellness is offered as our Renew and Repair protocol at $500 for a 5-week series. NAD+ is essential for metabolic function, slowing the aging process, supporting athletic function, boosting brain repair and cognitive function, reducing inflammation, and keeping your metabolism running efficiently to support weight loss.
What's Included in $500
- Initial consultation with Kristina Schafer, NP
- 5 weekly NAD+ injections (intramuscular or subcutaneous)
- Brief observation after each injection
- Ongoing symptom and progress monitoring
- Maintenance injections available at a per-injection rate
Insurance and Payment
NAD+ therapy is considered a wellness service and is generally not covered by insurance. HSA or FSA cards may be accepted at the account holder's discretion. CareCredit financing is accepted for qualifying patients.
Why Choose Riverstone Wellness for NAD+ Therapy in Easley, SC
Provider-led, time-honoring care
Internal Medicine Lens
NAD+ injections are guided by a true internal medicine clinician.
Honest About the Science
We share what is proven, what is promising, and what is still being studied.
Integrated Care
Coordinated with your primary care, mental health, and wellness plan.
Quick, Focused Visits
About 15 minutes per appointment for a clean, efficient injection experience.
Renew and Repair Protocol
$500 for a 5-week loading series, with maintenance options after
Provider-Designed Plans
Each protocol built around your goals: focus, recovery, anti-aging, or mood
Related Services
Combine NAD+ injections with other Riverstone Wellness therapies.
NAD+ Therapy FAQs
Common questions, honest answers
What is NAD+ therapy?
NAD+ therapy is the clinical injection of nicotinamide adenine dinucleotide, a coenzyme used by every cell for energy production and DNA repair. At Riverstone Wellness, we offer NAD+ as an intramuscular or subcutaneous injection only. We do not offer longer clinic-based NAD+ protocols. Kristina Schafer supervises each visit.
What does NAD+ do for the body?
NAD+ supports mitochondrial energy production, DNA repair, and sirtuin activity related to aging and metabolism. Patients use it for clarity, energy, anti-aging support, and recovery support.
Can NAD+ be given as an injection?
Yes. NAD+ can be delivered as an intramuscular or subcutaneous injection prepared by a licensed compounding pharmacy. At Riverstone Wellness, this is the only delivery method we offer for NAD+. The injection itself takes about 30 seconds, and your full visit runs around 15 minutes.
How long does an NAD+ injection take?
The injection itself takes about 30 seconds, followed by a brief observation period. From check-in to walk-out, plan on roughly 15 minutes.
Will I feel anything during or after the injection?
Most patients feel only a quick pinch at the injection site. Some notice a brief sense of warmth, mild flushing, a fluttery feeling in the chest, or mild nausea in the minutes after the dose. These effects ease quickly. Kristina monitors you during the observation period and adjusts future doses as needed.
How often should I get NAD+?
Most patients begin with a loading series of weekly injections for about 4 weeks, then move to maintenance every 2 to 4 weeks. Kristina personalizes the schedule based on your goals and how you feel between visits.
When will I notice results?
Many patients notice changes within 24 to 72 hours of their first injection, such as a quieter mind and steadier energy. Fuller benefit usually builds over the loading series and into maintenance.
Are there side effects?
NAD+ injections are generally well tolerated. Common, short-lived effects include flushing, brief chest pressure, mild nausea, headache, lightheadedness, or soreness at the injection site. Serious reactions are uncommon. Kristina screens you carefully and observes you after each dose.
Who should not get NAD+?
NAD+ therapy is not appropriate during pregnancy or breastfeeding, with active infection at the planned injection site, with a known allergy to NAD+ or compounded ingredients, or with severe heart, kidney, or liver disease without specialist clearance. It is also not a substitute for evaluation of new or worsening symptoms.
Can I combine NAD+ with other treatments?
Often, yes. NAD+ pairs naturally with primary care, mental health care, weight management, sermorelin therapy, and lifestyle coaching at Riverstone. Kristina coordinates your plan so each piece supports the others.
Location4891 Hwy 153 Unit E
Easley, SC, 29642
Easley, SC, 29642
Phone(864) 520-4474
Schedule Your NAD+ Therapy Consultation
References
- Rajman L, Chwalek K, Sinclair DA. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. PubMed PMID: 29514064. NAD+ levels decline with age and NAD+ boosting strategies have therapeutic potential in animal models of metabolic and neurodegenerative disease.
- Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. PubMed PMID: 31954472. Reviews the central role of NAD+ in cellular energy metabolism, DNA repair, and the aging process.
- Yoshino J, Baur JA, Imai SI. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. PubMed PMID: 29249689. Reviews oral NAD+ precursors and the rationale for raising NAD+ to support metabolic and tissue health.
- Reiten OK, Wilvang MA, Mitchell SJ, Hu Z, Fang EF. Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing. PubMed PMID: 32612241. Translational review of NAD+ precursor research from preclinical models through early human studies.
- National Institutes of Health, National Library of Medicine. NAD+ in aging and age-related disease. PubMed PMID: 31883094. Discusses how restoring NAD+ levels may support healthspan in aging tissues.